This review discusses the features of oligoarticular, polyarticular, systemic, and psoriatic JIA and enthesitis-related ...

A 77-year-old woman presented with a 2-day history of abdominal pain, nausea, and vomiting. CT of the abdomen revealed herniation of a loop of ileum that was inferior to the inguinal ligament and ...

Intravenous thrombolysis remains a standard treatment for acute ischemic stroke within 4.5 hours after onset. Vascular ...

Atrial fibrillation affects more than 33 million people worldwide and is a leading cause of stroke. 1 Alcohol consumption is ingrained in Western culture, with 57% of American adults drinking ...

The authors review the epidemiology, pathophysiology, and treatment of alcohol-associated hepatitis, including the evidence for glucocorticoids and liver transplantation.

Penicillin is the most common drug allergy identified in medical records, with a prevalence ranging from 6 to 25% across various regions and treatment populations. 5,6 Benign cutaneous reactions ...

Retinoblastoma is a childhood retinal cancer that occurs in approximately 6 of 100,000 live births, with 250 to 300 new cases per year in the United States and approximately 8000 worldwide. 1 ...

One third of people with epilepsy have seizures despite medical treatment. The authors examine wearable digital health devices that can detect seizures and how these devices can affect epilepsy care.

Most rotator-cuff tears are degenerative, atraumatic, and more prevalent with age. Nonoperative treatment, including physical therapy, is typically recommended; surgery is considered in some cases.

In this NEJM Outbreaks Update, Editor-in-Chief Eric Rubin and Deputy Editor Lindsey Baden are joined by Indiana Commissioner of Public Health Lindsay Weaver to discuss the current state of avian in ...

Patients with severe asthma are at increased risk for a decreased quality of life, fixed airway obstruction, hospitalization, and death. Biologics may be required to reduce the disease burden. This ...

Current therapies for recurrent Clostridioides difficile infection do not address the disrupted microbiome, which supports C. difficile spore germination into toxin-producing bacteria. SER-109 is a ...